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    Xilio Therapeutics, Inc.

    XLO
    NASDAQ
    Healthcare
    Biotechnology
    Waltham, MA, US64 employeesxiliotx.com
    $8.55
    +0.07(0.83%)

    Mkt Cap $49M

    $7.14
    $16.10

    52-Week Range

    At a Glance

    AI-generated

    Xilio Therapeutics, Inc., a clinical-stage biotech firm, reported total revenue of $43.8 million for FY 2025, a significant increase from $6.3 million in FY 2024, driven by collaboration and license revenue from agreements with AbbVie ($20.1 million) and Gilead ($23.6 million), including milestones.

    8-K
    Xilio Therapeutics announced fourth quarter and full year 2025 financial results on March 23, 2026, reporting collaboration and license revenue of $13.7 million for Q4 and net income of $10.4 million, alongside a cash position of $137.5 million as of December 31, 2025. The company provided pipeline updates on XTX501 and masked T cell engagers, with cash runway extended through the end of 2027.

    $49M

    Market Cap

    $3M

    Revenue

    —

    Net Income

    Employees64
    Fundamentals

    How The Business Makes Money

    Xilio Therapeutics, Inc., a clinical-stage biotechnology company, develops immunotherapies to improve the immune system of cancer patients. Its checkpoint inhibitor program includes XTX101, a clinical-stage, tumor-selective anti-CTLA-4 mAb that is in Phase 1/2 clinical trials in patients with solid tumors. The company also develops cytokine programs, which comprises XTX202, a modified form of IL-2; XTX301, an IL-12 product candidate; and XTX401, an IL-15 product candidate that are masked with a protein domain to prevent binding activity until cleaved off by tumor microenvironment (TME)-associated proteases. Xilio Therapeutics, Inc. was founded in 2016 and is headquartered in Waltham, Massachusetts.

    Industry Biotechnology
    Activity

    What Changed Recently

    Financial Results
    Mar 22, 2026

    Results of Operations and Financial Condition. On March 23, 2026, Xilio Therapeutics, Inc. (the “Company”) announced its financial results for the quarter and y

    Securities Modification
    Mar 11, 2026

    . Material Modification to Rights of Security Holders. To the extent required by Item 3.03 of Form 8-K, the information contained in Item 5.03 of this Current R

    Material Agreement
    Feb 11, 2026

    . Entry into a Material Definitive Agreement. On February 11, 2026, Xilio Therapeutics, Inc. (the “Company”) entered into an underwriting agreement (the “Underw

    Financial Results
    Jan 7, 2026

    of this Current Report on Form 8-K, including Exhibit 99.1, is being furnished and shall not be deemed “filed” for purposes of Section 18 of the Securities Exch

    Regulation FD
    Mar 8, 2026

    of this Current Report on Form 8-K, including Exhibit 99.1, is being furnished and shall not be deemed “filed” for purposes of Section 18 of the Exchange Act, o

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    Analyst View
    Company Profile
    CIK0001840233
    ISINUS98422T1007
    CUSIP98422T100
    Phone617 430 4680
    Address828 Winter Street, Waltham, MA, 02451, US
    SEC EDGAR

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