Milestone Scientific Inc.

This amendment materially advances Milestone Scientific’s near-term capital-raising strategy by restructuring key contractual conditions tied to BP4 S.r.l.—a shareholder holding 11.31% of the Company’s common stock—and its controlling party Innovest S.p.A. The revised ‘Qualified Offering’ definition establishes a clear, time-bound threshold ($900,000–$2.3M gross proceeds, based on March 17, 2026 closing price) that, if met, would trigger binding lock-up commitments from BP4, its affiliated parties, and key insiders—including all directors re-elected in December 2025 and all officers. The extension of the lock-up deadline to April 17 (or May 1) provides operational flexibility while signaling urgency around financing execution. Critically, the inclusion of United Systems and its affiliates among ‘Other Locked-Up Parties’ expands the pool of restricted shareholders beyond traditional insiders, potentially reducing near-term overhang risk. The $27,500 payment to BP4—explicitly tied to transaction-related disbursements and capped at $100,000—confirms ongoing cost allocation under the MOU but does not represent new consideration for equity or control. For investors, this filing signals active progress toward a financing event that could materially impact liquidity, dilution, and governance stability, particularly given BP4’s significant existing stake and consent/blockage rights.