APRE · Aprea Therapeutics, Inc.

Summary

Aprea Therapeutics, Inc. issued a press release on February 18, 2026, announcing the second unconfirmed partial response observed in a patient. This clinical update is disclosed under Item 8.01 Other Events and attached as Exhibit 99.1.

Key takeaways

• Press release issued February 18, 2026
• Second unconfirmed partial response (uPR) observed in a patient
• Item 8.01 Other Events
• Exhibit 99.1 Press Release