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8-K2026-03-25· x-ai/grok-4.1-fast

MAZE · Maze Therapeutics, Inc.

0001193125-26-122774

SEC filing

Summary

Maze Therapeutics reported fourth quarter and full year 2025 financial results with $360.0 million in cash supporting operations into 2028, announced positive Phase 2 HORIZON topline data for MZE829 showing 35.6% mean uACR reduction in broad AMKD patients, and appointed Neil Kumar as a Class I director effective March 27, 2026. These disclosures provide clinical proof-of-concept, financial visibility, and strengthened board expertise.

Key takeaways