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10-K2026-03-25· x-ai/grok-4.1-fast

BYSI · BeyondSpring Inc.

0001171843-26-001908

SEC filing

Summary

BeyondSpring Inc., a clinical-stage biopharmaceutical company, reported a net loss of $14.2 million for the fiscal year ended December 31, 2025. The loss before income tax from continuing operations was $8.6 million, with an income tax expense of $90 thousand. Total assets decreased to $25.9 million, including $7.8 million in cash and cash equivalents, $4.8 million in short-term investments, and $20.9 million in total current assets. Total liabilities stood at $49.9 million, driven by $28.6 million in deferred revenue and discontinued operations liabilities, resulting in a total shareholders' deficit of $24.0 million. Cash flows reflected heavy R&D investment, with net cash used in operating activities of $19.8 million, partially offset by $10.8 million provided by investing activities, mainly $7.4 million from the sale of subsidiary interests and $18.4 million from short-term investment maturities, and $5.0 million from financing activities including $2.0 million from ordinary share issuance. Net decrease in cash was $3.9 million. The company continues development of Plinabulin and its pipeline, with no revenue reported, emphasizing liquidity management amid ongoing clinical trials and discontinued operations.

Key takeaways

Full analysis

Performance Summary

BeyondSpring Inc. recorded a net loss of $14.2 million for FY 2025, starting from the cash flow statement reconciliation. Loss before income tax was -$8.6 million, with income tax expense of $90K after adjustments including changes in valuation allowance of -$577K and other items. No prior year figures are provided for direct comparison. Balance sheet shows total assets of $25.9M, down implicitly from operations, with shareholders' deficit of -$24.0M due to accumulated deficit of -$408.4M offset by $375.7M additional paid-in capital. Discontinued operations contribute $8.0M current assets and $11.1M current liabilities. Shares outstanding increased to 41,122,320 from 40,316,320 in 2024.

Revenue Analysis

No revenue figures are disclosed in the XBRL data or document content for FY 2025. As a clinical-stage biopharmaceutical company focused on Plinabulin and pipeline assets, operations remain pre-commercialization with expenses dominated by R&D contracts and no segment revenue breakdown provided.

Margins & Profitability

No gross profit, operating income, or margin metrics are available. Profitability is negative, reflected in the $14.2M net loss and $8.6M pre-tax loss, driven by R&D and operational costs. Share-based compensation was $722K, depreciation $87K, and non-cash lease expenses $747K in cash flow adjustments. Tax reconciliation shows effective rate impacts from preferential rates, R&D credits, and valuation changes.

Cash Flow & Balance Sheet

Net cash used in operating activities was -$19.8M, adjusted for $7.0M gain on subsidiary sale, $1.8M accrued expenses increase, and $722K share-based compensation. Investing provided $10.8M, including $7.4M subsidiary proceeds, $18.4M investment maturities minus $14.9M purchases. Financing yielded $5.0M from $2.0M share issuance and $2.7M noncontrolling contributions. Cash decreased $3.9M to $7.8M, with continuing operations cash at $15.3M excluding discontinued $2.4M. Liquidity includes $4.8M short-term investments; liabilities feature $28.6M deferred revenue and $36.3M noncurrent total.

Outlook

No specific management guidance on future financials is provided. Strategic focus remains on Plinabulin as a pipeline-in-a-drug for cancer, with pre-clinical immune agents and equity in SEED. Risks include funding needs, potential dilution, lease commitments through 2027, and government grant obligations for subsidiary Wanchunbulin until 2033. Critical estimates involve R&D accruals; ongoing clinical development may require additional capital.