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8-K2026-03-31· deepseek-chat

INKT · MiNK Therapeutics, Inc.

0001193125-26-133346

SEC filing

Summary

MiNK Therapeutics reported a net loss of $12.5 million for the full year 2025, ended the year with $13.4 million in cash, and outlined multiple clinical catalysts for 2026 across its iNKT cell therapy pipeline.

Key takeaways

Full analysis

MiNK Therapeutics' 2025 financial results reflect continued investment in its clinical-stage iNKT cell therapy platform, with a net loss of $12.5 million for the year, an increase from $10.8 million in 2024. The company ended 2025 with $13.4 million in cash and has since raised an additional $3.0 million, extending its financial runway through 2026. Management emphasized 2025 as a foundational year, sharpening focus on immune restoration in autoimmune and inflammatory diseases. The financial resources are directed toward a catalyst-rich 2026 pipeline, including the planned initiation of a Phase 2 trial for ARDS/hypoxemic pneumonia in the first half of 2026, with early data expected by year-end. This program targets a substantial market opportunity of approximately 200,000–300,000 patients annually in the U.S. and major European markets. The GVHD program is advancing with external non-dilutive funding from an NIH STTR grant and a philanthropic award, with a Phase 1 trial expected to dose its first patient in May 2026 and preliminary data anticipated in the second half of 2026. In oncology, data presented at SITC 2025 showed agenT-797 delivering durable clinical benefit in checkpoint-refractory solid tumors, with a median overall survival exceeding 23 months in combination with a PD-1 therapy. The company also secured a collaboration with the C-Further Consortium, providing up to $1.1 million in non-dilutive funding for the PRAME-TCR iNKT program in pediatric oncology. Operationally, MiNK appointed Melissa Orilall as Principal Financial Officer to strengthen financial leadership as the company transitions into a more execution-driven clinical-stage biopharmaceutical entity. The combination of clinical progress, non-dilutive funding inflows, and operational readiness positions MiNK for multiple near-term clinical milestones in 2026.