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8-K2026-05-07· grok-4-1-fast-non-reasoning

NMRA · Neumora Therapeutics, Inc. Common Stock

0001193125-26-210310

SEC filing

Summary

Neumora Therapeutics reported Q1 2026 financial results with reduced R&D and G&A expenses, a net loss of $53.5 million, and $147.1 million in cash supporting operations into Q3 2027, alongside pipeline progress.

Key takeaways

Full analysis

Neumora Therapeutics announced its first quarter 2026 financial results, showing meaningful cost reductions that narrowed the net loss to $53.5 million from $68.0 million in the prior year period. Research and development expenses declined 26% to $38.6 million, driven by lower clinical trial costs and personnel-related expenses, reflecting disciplined execution amid pipeline advancement. General and administrative expenses fell 24% to $14.3 million, also due to reduced personnel costs. CEO Paul L. Berns highlighted steady progress, including full enrollment in the navacaprant KOASTAL-2 and -3 studies for major depressive disorder, with joint topline data anticipated in Q2 2026 from over 450 optimized patients. The balance sheet remains robust with $147.1 million in cash and equivalents as of March 31, 2026, sufficient to fund operations into Q3 2027 without near-term dilution risk. Pipeline momentum continues with NMRA-511 advancing in Alzheimer's disease agitation after positive Phase 1b results showing strong effect size and favorable safety; multiple ascending dose data is due in H2 2026 ahead of a Phase 2 start in Q1 2027. NMRA-898's Phase 1 in schizophrenia and NMRA-215 for obesity are on track for H2 2026 updates and Q1 2027 clinic entry, respectively. These catalysts position Neumora to deliver multiple data readouts this year, potentially de-risking its novel neuroscience portfolio targeting underserved brain diseases.