0001178913-26-002744
SEC filingSilexion Therapeutics deepened Q1 net losses to $2.7M amid R&D ramp-up for the planned SIL204 human clinical trial in Q2 2026, with operating cash burn accelerating to $3.6M and a going concern warning highlighting urgent capital needs.
The operating cash burn intensified to $3.6 million from $2.5 million year-over-year, mirroring the push toward trial readiness. This increase stemmed primarily from higher prepayments to R&D product development subcontractors and consultants for GMP batch manufacturing of the drug product, positioning the company for trial initiation in Q2 2026. Free cash flow matched operating cash flow at -$3.6 million, given zero capital expenditures this quarter versus minimal $6K prior year.
Liquidity pressures are acute, with management and auditors expressing substantial doubt about continuing operations without additional external capital. Recent financing includes an ATM agreement entered in September 2025, though inflows remain limited. A proposed reverse share split aims to bolster the share price for Nasdaq listing continuity. Looking forward, R&D expenses are expected to rise further as clinical plans advance, with use of funds contingent on evolving business conditions and funding availability. Investors should monitor capital raises closely amid the going concern emphasis and trial milestones.