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This Amendment No. 1 to the Annual Report on Form 10-K for enGene Holdings Inc. for the fiscal year ended October 31, 2025, filed on February 19, 2026, amends and restates only Part III (Items 10, 11, 12, 13, and 14) and Part IV (Item 15) of the original filing. The amendment includes the Part III information previously omitted and adds new officer certifications. No financial statements are included or amended in this filing. The document provides detailed information on the company's directors, executive officers, corporate governance, executive compensation, security ownership, related transactions, and principal accounting fees. Key executive compensation for fiscal 2025 included total compensation of $5,758,289 for CEO Ronald H.W. Cooper, $2,216,126 for CFO Ryan Daws, and $3,151,902 for CMO Hussein Sweiti. The aggregate market value of common equity held by non-affiliates was $154,176,366 as of April 30, 2025, with 66,989,466 common shares outstanding as of February 17, 2026.